A similar finding was reported by Chong et al [18] This could be

A similar finding was reported by Chong et al.[18] This could be because of marginal breakdown of resin-modified zinc oxide eugenol and high polymerization shrinkage of LC GIC. However, Alhadainy and Himel[23] reported less dye penetration for LC GIC followed by Cavit �C a zinc oxide eugenol-based cement. According to them, the superiority of glass ionomer was because of www.selleckchem.com/products/Cisplatin.html its ability to adhere to dentin. In addition, LC GIC had good flow property that helped it seal the apical end of the furcal perforation. Materials versus positive control Highly significant results were found when the microleakage values for MTA and composite resin (except LC GIC and resin-modified zinc oxide eugenol) were compared using one-way ANOVA analysis and Student’s t-test.

The positive control group received no retrograde root filling in the retrograde root cavities. But, when LC GIC and resin-modified zinc oxide eugenol were compared with the positive control, although the mean values for microleakage with LC GIC and resin-modified zinc oxide eugenol were less, the difference found was non-significant. This could again be due to marginal breakdown of resin-modified zinc oxide eugenol and high polymerization shrinkage of LC GIC. Materials versus negative control Similarly, when MTA was compared with the negative control group using Student’s t-test, a highly significant relation was found. The negative control group did not allow any microleakage as the tip was also coated with two coats of nail polish. This was done to confirm that the experiment performed under standard conditions was showing true results.

CONCLUSION All the four materials used in the study showed some microleakage throughout the experimental period Of the four materials used, MTA displayed minimum microleakage while microleakage with resin-modified zinc oxide eugenol was found to be maximum LC GIC and resin-modified zinc oxide eugenol displayed almost similar values for dye leakage Except LC GIC, all the materials showed a constant non-significant increase in microleakage on being aged from 0 h to 1 week LC GIC showed an initial increase in microleakage till 72 h, which decreased at the end of 96 h, and again increased at 1 week, although these variations were statistically non-significant Thus, the sealing ability in terms of microleakage can be summarized as: MTA > Composite resin with dentin bonding agent > Light cured glass ionomer cement > Resin modified zinc oxide eugenol. Footnotes Dacomitinib Source of Support: Nil Conflict of Interest: None declared.
Male albino rats of Wistar Kyoto strain weighing about 200-220 g were procured from National Institute of Nutrition (NIN), Hyderabad, India. The animals were housed in solid bottom polypropylene cages.

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