: Genome-wide association study for crohn’s disease in the quebec founder population identifies multiple validated disease loci. Proc Natl Acad Sci USA 2007,104(37):14747–14752.PubMedCrossRef

29. Gradel KO, Nielsen HL, Schonheyder HC, Ejlertsen T, Kristensen B, Nielsen H: Increased short- and long-term risk of inflammatory bowel disease after salmonella or campylobacter gastroenteritis. Gastroenterology 2009,137(2):495–501.PubMedCrossRef 30. Krishnaraju K, Hoffman B, Liebermann DA: The zinc finger transcription factor egr-1 activates macrophage differentiation in m1 myeloblastic leukemia cells. Blood 1998,92(6):1957–1966.PubMed 31. Hardt WD, Chen LM, Schuebel KE, Bustelo XR, Galan JE: S. Typhimurium encodes an activator of rho gtpases that induces membrane ruffling and nuclear responses in host cells. Cell 1998,93(5):815–826.PubMedCrossRef 32. Boyle EC, Brown NF, Finlay BB: Salmonella enterica serovar typhimurium effectors sopb, sope, sope2 and sipa selleckchem disrupt tight junction this website structure and function. Cell Microbiol 2006,8(12):1946–1957.PubMedCrossRef 33. Bruno VM, Hannemann S, Lara-Tejero M, Flavell RA, Kleinstein SH, Galan JE: Salmonella typhimurium type iiisecretion effectors stimulate innate immune responses in cultured epithelial cells. Plos Pathog 2009,5(8):E1000538.PubMedCrossRef 34. Hapfelmeier S, Ehrbar K, Stecher B, Barthel M, Kremer

M, Hardt WD: Role of the salmonella pathogenicity island 1 effector proteins sipa, sopb, sope, and sope2 in salmonella enterica subspecies 1 serovar typhimurium colitis in streptomycin-pretreated mice. Infection and Immunity 2004,72(2):795–809.PubMedCrossRef 35. Liao AP, Petrof EO, Kuppireddi XL184 S, Zhao Y, Xia Y, Claud EC, Sun J: Salmonella type iii effector avra stabilizes cell tight junctions to inhibit inflammation in intestinal epithelial cells. Plos One 2008,3(6):E2369.PubMedCrossRef 36. Wang X, D’Andrea AD: The interplay of fanconi anemia proteins in the dna damage response. Dna Repair (Amst) 2004,3(8–9):1063–1069.CrossRef 37. Meetei AR, Yan Z, Wang W: Fancl replaces brca1 as the likely ubiquitin ligase responsible for fancd2 monoubiquitination. Cell Cycle 2004,3(2):179–181.PubMedCrossRef 38. Fei P, Yin J, Wang W: New advances

in the dna damage response network of fanconi anemia and brca proteins. faap95 replaces brca2 as the true fancb protein. Cell Cycle 2005,4(1):80–86.PubMedCrossRef 39. Dey BR, Spence SL, Nissley P, Furlanetto Sulfite dehydrogenase RW: Interaction of human suppressor of cytokine signaling (socs)-2 with the insulin-like growth factor-i receptor. The Journal of Biological Chemistry 1998,273(37):24095–24101.PubMedCrossRef 40. Hilton DJ, Richardson RT, Alexander WS, Viney EM, Willson TA, Sprigg NS, Starr R, Nicholson SE, Metcalf D, Nicola NA: Twenty proteins containing a c-terminal socs box form five structural classes. Proc Natl Acad Sci USA 1998,95(1):114–119.PubMedCrossRef 41. Chen XP, Losman JA, Rothman P: Socs proteins, regulators of intracellular signaling. Immunity 2000,13(3):287–290.