PubMedCrossRef 8. Jones PA, Baylin SB: The epigenomics of cancer. Cell 2007, 128:683–692.PubMedCentralPubMedCrossRef 9. Feinberg selleck AP, Tycko B: The history of cancer epigenetics. Nat Rev Cancer 2004,
4:143–153.PubMedCrossRef 10. Zitt M, Zitt M, Müller HM: DNA MGCD0103 cell line methylation in colorectal cancer–impact on screening and therapy monitoring modalities? Dis Markers 2007, 23:51–71.PubMedCentralPubMedCrossRef 11. Kondo Y, Issa JP: Epigenetic changes in colorectal cancer. Cancer Metastasis Rev 2004, 23:29–39.PubMedCrossRef 12. De Maat MF, van de Velde CJ, van der Werff MP, Putter H, Umetani N, Klein-Kranenbarg EM, Turner RR, Van Krieken JHJM, Bilchik A, Tollenaar RAEM, Hoon DSB: Quantitative analysis of methylation of genomic loci in early-stage rectal cancer predicts distant recurrence. J Clin Oncol 2008, 26:2327–2335.PubMedCrossRef 13. Hartmann O, Spyratos F, Harbeck N, Dietrich D, Fassbender A, Schmitt M, Eppenberger-Castori S, Vuaroqueaux V, Lerebours F, Welzel K, Maier S, Plum A, Niemann S, Foekens JA, Lesche R, Martens JW: DNA methylation markers predict
outcome in node-positive, estrogen receptor-positive breast selleck chemical cancer with adjuvant anthracycline-based chemotherapy. Clin Cancer Res 2009, 15:315–323.PubMedCrossRef 14. Richiardi L, Fiano V, Vizzini L, De Marco L, Delsedime L, Akre O, Tos AG, Merletti F: Promoter methylation in APC, RUNX3, and GSTP1 and mortality Amylase in prostate cancer patients. J Clin Oncol 2009, 27:3161–3168.PubMedCrossRef 15. Di Domenico M, Santoro A, Ricciardi C, Iaccarino M, Iaccarino S, Freda M, Feola A, Sanguedolce F, Losito S, Pasquali D, Di Spiezio Sardo A, Bifulco G, Nappi C, Bufo P, Guida M, De Rosa G, Abbruzzese A, Caraglia M,
Pannone G: Epigenetic fingerprint in endometrial carcinogenesis: the hypothesis of a uterine field cancerization. Cancer Biol Ther 2011, 12:447–457.PubMedCrossRef 16. Issa JP: CpG island methylator phenotype in cancer. Nat Rev Cancer 2004, 4:988–993.PubMedCrossRef 17. Rashid A, Issa JPJ: CpG island methylation in gastroenterologic neoplasia: a maturing field. Gastroenterology 2004, 127:1578–1588.PubMedCrossRef 18. Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, Faasse MA, Kang GH, Widschwendter M, Weener D, Buchanan D, Koh H, Simms L, Barker M, Leggett B, Levine J, Kim M, French AJ, Thibodeau SN, Jass J, Haile R, Laird PW: CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006, 38:787–793.PubMedCrossRef 19. Hinoue T, Weisenberger DJ, Pan F, Campan M, Kim M, Young J, Kim M, Young J, Whitehall VL, Leggett BA, Laird PW: Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling. PLoS One 2009, 4:e 8357.CrossRef 20.