2 INCB024360 datasheet T-helper 1 cell differentiation     Apoptosis 12.5 negative regulation of

LPS-mediated signaling pathway     Adipocytokine signaling pathway 12.3 negative regulation of smooth muscle cell migration     Prostate cancer 11.4 regulation of MAP kinase activity chemotaxis     Toll-like receptor signaling pathway 11.1 protein amino acid dephosphorylation     T cell receptor signaling pathway 10.5 neutrophil activation     B cell receptor signaling pathway 9.9 entrainment of circadian clock   6 Phosphatidylinositol signaling system 32.2 anti-apoptosis click here No significant GO   Epithelial cell signaling in Helicobacter pylori infection 15.5 regulation of retroviral genome     Small cell lung cancer 14.2 replication     Pathways in cancer 12.4 T-helper 1 cell differentiation     Apoptosis 11.6 neutrophil activation     Adipocytokine signaling pathway 10.1 negative regulation of I-kappaB     Toll-like receptor signaling pathway 8.9 kinase/NF-kB cascade     MAPK signaling pathway 8.7 induction of positive chemotaxis     Bladder cancer 8.5 myeloid dendritic cell differentiation     B cell receptor signaling pathway 8.3     12 Leukocyte transendothelial migration 309.7 cell cycle arrest response to unfolded protein   Cell adhesion molecules (CAMs)

75.4 amino acid transport S-adenosylmethionine biosynthetic process   DNA replication 25.0 positive regulation of transcription     Cell cycle 20.0 response to stress     Pathways in cancer 19.4 regulation of MAP kinase activity     SPTLC1 p53 signaling pathway 17.0       Antigen processing and presentation Sepantronium research buy 15.7       MAPK signaling pathway 13.2       Small cell lung cancer 12.2       Circadian rhythm 11.9     24 Leukocyte transendothelial migration 80.3 keratinocyte differentiation cholesterol biosynthetic process   Cell cycle 24.4 amino acid transport response to unfolded protein   p53 signaling pathway 20.9 keratinization isoprenoid biosynthetic process   Circadian rhythm 18.6 angiogenesis creatine biosynthetic process   DNA replication 18.0 apoptosis response to oxidative stress   Adherens junction 16.1 response to stress     Pathways in cancer 14.9 cell cycle arrest     Nucleotide excision repair 14.3 pyrimidine nucleotide

metabolic     Ubiquitin mediated proteolysis 14.2 process     Phosphatidylinositol signaling system 13.7 induction of positive chemotaxis   Significantly impacted KEGG cellular pathways and enriched Gene Ontology terms (biological processes only) (p < 0.05) at different time points following co-culture of H. pylori and AGS cells. Top 10 pathways/ontologies included where number exceeds 10. IF = impact factor Because GO analysis simply associates differentially expressed genes with the ontologies, there is no attempt at ranking the true biological significance of individual genes or ontologies. Therefore, we included only genes with a log2FC > 1.5 in the GO analysis, excluding lesser significantly expressed genes that were likely to result in erroneous GO ranking.