Any significant effects were then followed up with post hoc t-tests where appropriate. Analysis of sensitivity data demonstrated a significant Task × Ear interaction [F  (1, 130) = 249.16, p   < .001, ηp2 = .657]. A partial eta squared ( ηp2) of .657 indicated that the strength of this relation was large based on Cohen’s

(1988) recommendation that small, medium, and large effects are reported as .01, .06, and .14, respectively. The interaction itself showed that participants performed better when words were delivered to the right ear rather than to the left as depicted in Fig. 1 and confirmed by post hoc tests [t  (132) = −10.21, p   < .001, ηp2 = .443]. t  -tests also revealed that participants were more accurate in detecting emotions that were delivered to their left, rather than to their right ear [t  (132) = 8.07, p   < .001, ηp2 = .332]. Task × Ear × SPQ EX-527 did not approach significance, indicating that this typical pattern of laterality was observed across both schizotypy groups [F  (1, 130) = .08, p   > .05, ηp2 = .001, see Table 2]. A significant main effect of SPQ [F  (1, 130) = 8.05, p   = .005, ηp2 = .058] indicated that discrimination differences exist between the two groups. The low schizotypy group demonstrated higher sensitivity in detecting targets overall [M   = 2.15, SD   = .631]

Belinostat clinical trial compared to the high schizotypy group [M   = 1.93, SD   = .615]. Thus, although the high schizotypal

personality group displayed typical laterality patterns, its discrimination ability was reduced in relation to the low group. A significant Task × SPQ interaction [F  (1, 130) = 4.19, p   = .043, ηp2 = .031] revealed that the low schizotypy group had better discrimination on the ‘emotion’ task than the high schizotypy group [t  (130) = 2.85, p   = .005, ηp2 = .059] (see Fig. 2). The partial eta squared reinforces that the magnitude of the difference in mean scores between the groups was small to moderate. In contrast, no significant differences were found between the groups in the ability to accurately detect word targets [t  (130) = 1.22, p   > .05, ηp2 = .011]. The low schizotypal personality group also demonstrated more accurate discrimination for ‘emotion’ targets than Demeclocycline ‘word’ targets [t  (67) = −2.66, p   = .010, ηp2 = .095], whereas the high schizotypy group showed no differences on the performance of these tasks [t  (63) = .418, p   > .05, ηp2 = .002]. The analysis of mean reaction time mirrored the significant Task × Ear interaction and the large magnitude of effects [F  (1, 130) = 62.38, p   < .001, ηp2 = .324] that were observed in the accuracy data (see Fig. 3). Specifically, reaction times were faster for word targets presented to the right ear [t  (131) = 5.47, p   < .001, ηp2 = .186], and for emotion targets presented to the left ear [t  (131) = −4.58, p   < .001, ηp2 = .138].