“Background: Adjustment difficulties of college students are common and their school adjustment has gained wide concern in recent years. Negative life events and psychological capital (PsyCap) have been associated with school adjustment. However, the potential impact of negative life events on PsyCap, and whether PsyCap mediates the relationship between negative life events and school
adjustment among nursing students have not been studied. Objectives: To investigate the relationship among negative life events, PsyCap, BI 2536 solubility dmso and school adjustment among five-year vocational high school nursing students in China and the mediating role of PsyCap between negative life events and school adjustment
Design: A cross-sectional survey design was conducted. Participants and settings: 643 five-year vocational high school nursing students were recruited from three public high vocational colleges in Shandong of China. Methods: Adolescent Self-Rating Life Event Checklist (ASLEC), the Psychological Capital Questionnaire for Adolescent Students scale (PCQAS), and the Chinese College Student Adjustment Scale (CCSAS) were used in this study. Hierarchical linear regression analyses were performed to explore the mediating role of PsyCap. Results: Negative life events were negatively associated with the dimensions of school adjustment (interpersonal relationship adaptation, learning adaptation, DAPT mw campus life adaptation, career adaptation, emotional adaptation, self-adaptation, and degree of satisfaction). PsyCap was positively associated with the dimensions of school adjustment and negatively associated with negative life events. PsyCap partially mediated the relationship between negative life events and school adjustment Conclusions: Negative life events may increase
the risk of school maladjustment in individuals with low PsyCap. Interventions designed to increase nursing students’ PsyCap might buffer the stress of adverse life events, and thereby, enhance students’ positive adjustment to school. (C) 2015 Elsevier Ltd. All rights reserved.”
“Methamphetamine (Meth) abuse can result in long-lasting https://www.selleckchem.com/products/jq1.html psychosis and dependence. The nucleus accumbens (NAc), which controls psychomotor and reward behaviours, is an important interface between the limbic system and receives convergent projections from dopaminergic and glutamatergic terminals. This study investigated the involvements of dopaminergic and glutamatergic transmission in the development of Meth psychosis and dependence by using tyrosine hydroxylase heterozygous mutant (TH+/-) mice and N-methyl-D-aspartate receptor knockout (NR2A(-/-)) mice. Repeated treatment with Meth (1 mg/kg s.c.