Methods: Eleven fresh-frozen cadaveric knees were loaded to 1000

Methods: Eleven fresh-frozen cadaveric knees were loaded to 1000 N of axial load at 0 degrees, 30 degrees, 60 degrees, and 90 degrees of flexion with use of a custom testing apparatus attached to a materials testing machine. Tibiofemoral translations and internal-external and varus-valgus rotations were unconstrained. The knees were tested under four conditions: intact, medial meniscal tear, repaired meniscal tear, and total medial meniscectomy. Radial split tears were created in six knees, and vertical tears were

created in five knees. Pressure-sensitive film was used to measure tibiofemoral contact pressure and area.

lateral compartments that were not significantly different from those associated with total medial meniscectomy. The exception was at 90 degrees, where the lateral compartment pressure associated with the vertical tear of the medial meniscus was higher than that associated with total medial meniscectomy. In general, after repair of the vertical tear, contact pressure and area values were similar to those in the intact condition.

Conclusions: Radial split tears of the medial

meniscus that extend from the inner rim to the peripheral third of the www.selleckchem.com/products/MS-275.html meniscus do not cause significant changes in joint contact area and pressure. Vertical tears of the medial meniscus cause nonsignificant increases in joint contact pressure and reductions in contact area in the medial and lateral compartments. Repair of the vertical tear reverses these selleck kinase inhibitor contact changes, resulting in contact pressure and area similar to the intact state.”
“The exchange interactions for rapidly solidified (Nd/Pr)(Fe/Co)B hard magnetic alloys with remanence enhancement were studied by analyzing characteristic magnetic curves and Henkel plots. The exchange coupling can be improved by increasing soft phase content within hard matrix. With increasing temperature, the exchange interaction is enhanced due to the increased exchange length. An increased recoil susceptibility was found for the alloys with improved exchange coupling. Analysis of the microstructure parameters indicated that Co substituting Fe and introducing soft alpha-(Fe,Co) phase not only reduce the stray field effects but also enhance the exchange interaction. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3072717]“
“SETTING: Although a preventable and treatable disease, tuberculosis (TB) is among the top 10 causes of death worldwide. A consequence of inadequately treated drug-susceptible TB (DS-TB) is multidrug-resistant TB (MDR-TB).

Cathepsin K

Cathepsin K is a cysteine protease expressed predominantly in osteoclasts

Methods: Eleven fresh-frozen cadaveric knees were loaded to 1000