The compound was prepared as per the general procedure mentioned above purified and isolated as colorless solid; yield 76.10%; mp 186 °C; IR (KBr) vmax 2988, 1170, 750, 550 cm−1; 1H NMR (CDCl3) δ ppm; 7.28–8.10 (m, 10H, Ar–H), 2.01 (s, 3H, SCH3); 13C NMR (CDCl3) δ ppm; 158.2, 141.3, 139.2, 139.1, 138.2, 137.2, 35.2, 132.1, 131.2, 131.1, 129.1, 129.0, 128.1, 127.7, 127.4, 127.1, 126.1, 124.2, 118.2, 15.2; HRMS (EI) m/z calcd for C22H13BrCl2N2S2: 517.9081; found: 517.9077. This compound was prepared as per the above mentioned procedure Decitabine purified and isolated as pale yellow solid: yield 91.38% mp 209 °C; IR (KBr) vmax 2966, 1477, 1320, 765 cm−1; 1H NMR (CDCl3) δ ppm; 7.21–8.0 (m, 11H, Ar–H), 3.80 (s, 6H, OCH3); 13C NMR (CDCl3) δ ppm; 162.3, 157.2, 139.3, 138.3, 137.2, 132.3, 131.3, 129.3, 128.3, 125.2, 125.0, 123.5, 122.3, 115.2, 56.2; HRMS (EI) m/z calcd for C23H17ClN2O2S: 420.0699; found: 420.0694. The compound was prepared as per the general procedure mentioned above purified and isolated as colorless solid; yield 89.15%; mp 196 °C; IR (KBr) vmax 2978, 1320, 1170, 750, cm−1; 1H NMR (CDCl3) δ ppm; 7.10–7.68 (m,10H, Ar–H), 2.31 (s, 3H, SCH3); 13C NMR (CDCl3) δ ppm;

158.1, Selisistat 141.2, 139.2, 138.2, 137.2, 136.2, 135.2, 132.1, 130.2, 129.6, 129.0, 129.7, 128.7, 127.5, 127.1, 127.0, 125.2, 124.3, 122.4, 15.8; HRMS (EI) m/z calcd for C22H13Cl3N2S2: 473.9586; found: 473.9581. The compound was prepared as per the general procedure mentioned above purified and isolated as yellow solid; yield 76.00%; mp 214 °C; IR (KBr) vmax 2869,1496, 1290, 750 cm−1; 1H NMR (CDCl3) δ ppm; 7.28–8.16 (m, 10H, Ar–H),

2.43, 2.72 (s, 6H, CH3); 13C NMR (CDCl3) δ ppm; 158.2, 140.3, 137.2, 136.2, 135.2, 135.0, 134.2, 132.3, 130.9, 130.4, 130.0, 129.8, 129.2, 128.4, 128.0, 127.6, 126.4, 125.4, 125.0, 122.3, 22.4, 21.3, 18.6; HRMS (EI) m/z calcd for C23H16 Cl2 N2 S: 422.0411found: 422.0407. All authors have none to declare. The authors Dr. Jitender K Malik would like to thank to Dr. Malleshappa Noolvi and Director General, Department of Science and Technology, New Delhi for funding the project (Grant. No. SR/FT/LS-0024/2008). Oxygenase “
“The heterocyclic system containing benzotriazole moieties system is of wide interest because of their diverse biological activities1 and 2 including anticonvulsant and anti-inflammatory activities,3 diuretic,4 analgesic,5 pesticidal.6 Recent publications reported synthetic protocols in solvent-less conditions7, 8 and 9 and in presence of ultrasonic radiation.10, 11, 12 and 13 Anthelmintic infections are now being recognized as cause of much chronic ill health amongst the tropical people.