The use of conjugated enynes circumvented possible side rections, such as oligomerizations and cyclotrimerizations. The isolation of reaction intermediate complexes revealed that the eta(3)-butadienyl coordination

is the key for the selective formation of cyclobutene.”
“Objective: Faith Moves Mountains assessed the effectiveness of a faith-placed lay health advisor (LHA) intervention to increase Papanicolaou (Pap) test use among middle-aged and older women in a region disproportionately affected by cervical cancer and low screening rates (regionally, only 68% screened in prior 3 years).\n\nMethod: This community-based RCT was conducted in four Appalachian Kentucky counties (December 2005-June 2008). Women aged 40-64 and overdue for screening were recruited from churches and Liproxstatin-1 research buy individually randomized to treatment (n = 176) or wait-list control

(n = 169). The intervention provided LHA home visits and newsletters addressing barriers to screening. Self-reported Pap test receipt was the primary outcome.\n\nResults: Intention-to-treat analyses revealed that treatment group participants (17.6% screened) had over twice the odds of wait-list controls (11.2% screened) of reporting Pap test receipt post-intervention, OR = 2.56, 95% Cl: 1.03-638, p = 0.04. Independent of group, recently screened participants (last Pap >1 but <5 years ago) had significantly higher odds of obtaining screening during the study than rarely or never screened participants (last Pap >= 5 years ago), OR = 2.50. 95% Cl: 1.48-425, p = 0.001.\n\nConclusions: The intervention was associated Selleck BIX01294 Navitoclax mouse with increased cervical cancer screening. The faith-placed LHA addressing barriers comprises a novel approach to reducing cervical cancer disparities among Appalachian women. (C) 2012 Elsevier Inc. All rights reserved.”
“Background. Definitive evidence that exercise interventions that improve gait also reduce disability is lacking. A task-oriented, motor sequence learning exercise intervention has been shown to reduce the energy cost of walking and improve gait speed, but whether the

intervention also improves activity and participation has not been demonstrated.\n\nObjective. The objective of this study was to compare the impact of a task-oriented, motor sequence learning exercise (TO) intervention and the impact of an impairment-oriented, multicomponent exercise (IO) intervention on activity and participation outcomes in older adults with mobility limitations. The mediating effects of a change in the energy cost of walking on changes in activity and participation also were determined.\n\nDesign. This study was a single-blind, randomized controlled trial.\n\nSetting. The study was conducted in an ambulatory clinical research training center.\n\nParticipants. The study participants were 47 older adults (mean age = 77.2 years, SD = 5.5) with slow and variable gait.