This is the first randomly selected sample of off-label and unlicensed prescribing from a major teaching hospital in Australia. No similar study has been published. Off-label learn more prescribing was higher for inpatients, compared with outpatients or emergency department patients. Patients in Australia will be exposed to drugs, doses or formulations which have not been evaluated

for licensing in that paediatric population. The current system of licensing drugs requires legislative change so that when a substantial evidence-base is available for a drug’s efficacy and safety it is incorporated with the license otherwise there will continue to be inadequate evidence of prescribing especially in paediatrics in Australia. 1. Therapeutics Goods Administration. Therapeutics Goods Administration – Product Information Search Facility, 2008 ongoing. Australia: Australian Government. (https://www.ebs.tga.gov.au/).

2. MIMS Australia. Monthly Index of Medical Specialities (eMIMS) 2008. E. Kiteterea, A. Jonesa, T. Evansa, Y. Jania,b aUCLH NHS Foundation Trust, London, UK, bUCL School of Pharmacy, London, UK Discharge summaries should include documentation of medication changes. All patients should be discharged with at least 2 weeks supply of medication. Ninety-five per cent of patients were discharged with at least 2 weeks supply of medication and 56% of discharge summaries had complete documentation of medication changes. Further work is required to ensure all discharge summaries are completed with adequate documentation and all patients are histone deacetylase activity discharged with at least 2 weeks supply of medication. A discharge summary is the communication of clinical information from the hospital to the GP and patient. Standards of discharge summaries include documentation of any changes to the patient’s regular medication, any newly started medication and any stopped medication with documentation of reasons for these changes. At our organisation, the discharge policy states that on discharge from the hospital, patients should have at least 2 weeks

supply of their long Dichloromethane dehalogenase term medication. This supply may be from the hospital – either as a near patient dispensing (NPD) supply or to take away (TTA) supply – or from the patient’s own supply of medication (POD) – either on the ward or at home. The aim of this audit was to assess whether the standards for documentation of medication changes on discharge summaries were being met, and to assess whether patients had at least two weeks supply of regular medication on discharge, as per hospital policy. The standards were 100% of discharge summaries should include documentation of changes to medication and 100% of patients should be discharged with at least 2 weeks supply of medication. Data were collected over seven working days, from all but one of the inpatient sites at our organisation. Maternity, critical care and paediatric wards were excluded.